Soon, diagnostic pill that could help detect stomach cancer

Washington – Researchers have developed a tiny capsule that could carry out a chemical analysis of the contents of one’s stomach and identify presence of so-called “occult” blood at very low levels.

Hongying Liu, Panpan Qiao, Xueli Wu, Lan Zhu, Xitian Pi and Xiaolin Zheng of Chongqing University, in China, have adapted capsule endoscopy to allow them to detect tiny quantities of blood that might be present in a patient with the earliest signs of stomach cancer.

The capsule is encased in non-toxic and acid-safe polycarbonate. It carries inside it a detector, power supply, and wireless transmitter.

The device has a detection limit of 6 micrograms per liter of fluid and laboratory tests demonstrate its simplicity as well as its reliability.

Once its task is complete the tiny pill-like device would be disposed of through the usual route without harm to the stomach or intestine. This approach thus avoids the uncomfortable and risk retrieval of such a device via the oral route.

Occult bleeding is usually first identified in patients who have given a stool sample in which blood is found. However, it is important to identify the source of such blood, whether intestine or stomach.

Details of the invention and initial trials are set to be published in the International Journal of Biomedical Engineering and Technology.